Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S2 family.
MRPS2; mitochondrial ribosomal protein S2; 28S ribosomal protein S2, mitochondrial; CGI 91; 28S ribosomal protein S2 mitochondrial; mitochondrial; 28S ribosomal protein S2; CGI91; Mitochondrial 28S ribosomal protein S2; MRP S2; MRP-S2; OTTHUMP00000022545; OTTHUMP00000022546; RT02_HUMAN; S2mt; CGI-91; zgc:158760