Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.
MRPL3; mitochondrial ribosomal protein L3; RPML3; 39S ribosomal protein L3, mitochondrial; MRL3; L3mt; Mitochondrial 39S ribosomal protein L3; mitochondrial 60S ribosomal protein L3; mitochondrial ribosomal protein; MRP-L3; COXPD9; fj61d01; zgc:66423; wu:fj61d01