Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.
MRPL23; mitochondrial ribosomal protein L23; RPL23L; 39S ribosomal protein L23, mitochondrial; L23MRP; L23 mitochondrial-related protein; L23mt; MRP-L23; Ribosomal protein L23-like; ribosomal protein related to L23 (mitochondrial); RPL23; FLJ45387; zgc:86630