Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
MRPL15; mitochondrial ribosomal protein L15; 39S ribosomal protein L15, mitochondrial; HSPC145; L15mt; MRP L7; MRP L15; RPML7; 39S ribosomal protein L15; 39S ribosomal protein L15 mitochondrial; MRPL 15; RPML 7; OTTHUMP00000226445; OTTHUMP00000226575; MRP-L7; MRP-L15; zgc:92856