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mrpl10

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Official Full Name
mitochondrial ribosomal protein L10
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.
Synonyms
MRPL10; mitochondrial ribosomal protein L10; 39S ribosomal protein L10, mitochondrial; 39S ribosomal protein L10; mitochondrial; L10MT; MGC17973; MRP L8; MRP L10; MRPL8; RPML8; 39S ribosomal protein L10 mitochondrial; 39S ribosomal protein L10 mitochondrial precursor; MRPL 10; L8mt; 39S ribosomal protein L8, mitochondrial; MRP-L8; MRP-L10; zgc:112529

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