Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER

mre11a

Bookmark and Share
Official Full Name
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Background
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3 to 5 exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3 to 5 exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
MRE11A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); ATLD; HNGS1; MRE11; MRE11B; double-strand break repair protein MRE11A; AT-like disease; MRE11 homolog 1; MRE11 homolog A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; DNA recombination and repair protein; meiotic recombination (S. cerevisiae) 11 homolog A , MRE11; AT like disease; double-strand break repair protein MRE11; meiotic recombination 11 homolog A (S. cerevisiae); zgc:64018; wu:fc38f05; wu:faa63d12; fc38f05