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mnt

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Official Full Name
MAX network transcriptional repressor
Background
The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.
Synonyms
MNT; MAX binding protein; max-binding protein MNT; bHLHd3; MAD6; Max interacting protein; MXD6; myc antagonist; ROX; Myc antagonist MNT; Max binding protein MNT; OTTHUMP00000115723; Max-interacting protein; class D basic helix-loop-helix protein 3

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