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mmp17

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Official Full Name
matrix metallopeptidase 17 (membrane-inserted)
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008]
Synonyms
MMP17; matrix metallopeptidase 17 (membrane-inserted); MT4-MMP; matrix metalloproteinase-17; MMP-17; MT4MMP; MTMMP4; MT-MMP 4; membrane-type matrix metalloproteinase 4; membrane-type-4 matrix metalloproteinase; matrix metalloproteinase 17 (membrane-inserted)

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