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mmp16

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Official Full Name
matrix metallopeptidase 16 (membrane-inserted)
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein activates MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16. [provided by RefSeq, Oct 2010]
Synonyms
MMP16; matrix metallopeptidase 16 (membrane-inserted); MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP; matrix metalloproteinase-16; MMP-16; MT3MMP; MTMMP3; MT-MMP 3; Putative transmembrane protein C8orf57; membrane-type matrix metalloproteinase 3; membrane-type-3 matrix metalloproteinase; C8orf57, chromosome 8 open reading frame 57 , matrix metalloproteinase 16 (membrane inserted); DKFZp761D112; MT3 MMP; membrane type-matrix metalloproteinase; matrix metalloproteinase 16 (membrane-inserted)