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micu1

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Official Full Name
mitochondrial calcium uptake 1
Background
This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]
Synonyms
MICU1; mitochondrial calcium uptake 1; CALC; EFHA3; MPXPS; CBARA1; calcium uptake protein 1, mitochondrial; ara CALC; atopy-related autoantigen CALC; calcium-binding atopy-related autoantigen 1; zgc:162148; calcium-binding atopy-related autoantigen 1 homolog

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