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mgll

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Official Full Name
monoglyceride lipase
Background
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of;monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several;physiological processes including pain and nociperception through hydrolysis of the endocannabinoid;2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively;spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
MGLL; monoglyceride lipase; monoacylglycerol lipase; Mgl; Magl; AA589436; HU K5; lysophospholipase homolog; HUK5; HU-K5; cb909; zgc:56561; wu:fc66g01