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me1

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Official Full Name
protocadherin beta 16
Background
This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3 exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
Synonyms
PCDHB16; protocadherin beta 16; protocadherin beta-16; cadherin ME1; KIAA1621; ME1; PCDH BETA16; PCDH3X; PCDHB8a; PCDHbeta 16; protocadherin 3x; ME 1; PCDBG_HUMAN; PCDH 3X; PCDH-beta-16; PCDHB 16; PCDHB 8a; Protocadherin beta 8a; Protocadherin-3X; Protocadherin3x; OTTHUMP00000160005; PCDH-BETA16