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mcc

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Official Full Name
mutated in colorectal cancers
Background
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
MCC; mutated in colorectal cancers; colorectal mutant cancer protein; DKFZp762O1615; FLJ38893; FLJ46755; MCC 1; MCC1; Protein MCC; OTTHUMP00000159017; OTTHUMP00000222860; OTTHUMP00000223206