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masp2

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Official Full Name
mannan-binding lectin serine peptidase 2
Background
The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases.
Synonyms
MASP2; mannan-binding lectin serine peptidase 2; mannan binding lectin serine peptidase 1 pseudogene 1 , mannan binding lectin serine protease 1 pseudogene 1 , mannan binding lectin serine protease 2 , MASP1P1; mannan-binding lectin serine protease 2; Mannan binding lectin serine peptidase 2; Mannan binding lectin serine protease 2; Mannose binding protein associated serine protease 2; MAP 19; MAP19; MASP 2; MBL associated plasma protein of 19 kD; MBL associated serine protease 2; Small MBL associated protein; sMAP; small MBL-associated protein; MBL-associated serine protease 2; MBL-associated plasma protein of 19 kD; mannan-binding lectin serine protease 1 pseudogene 1; mannose-binding protein-associated serine protease 2; mannan-binding lectin serine peptidase 1 pseudogene 1; MASP-2; MASP1P1; mannan-binding lectin associated serine protease 2; sb:eu714; wu:fb62a09

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