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march9

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Official Full Name
membrane-associated ring finger (C3HC4) 9
Background
MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).
Synonyms
MARCH9; membrane-associated ring finger (C3HC4) 9; E3 ubiquitin-protein ligase MARCH9; FLJ36578; RNF179; FLJ36578; BC019560; E3 ubiquitin protein ligase MARCH9; MARCH IX; Membrane associated RING CH protein IX; membrane associated ring finger (C3HC4) 9; Membrane associated RING finger protein 9; RING finger protein 179; RNF179; OTTHUMP00000243862; RING finger protein 179; membrane-associated RING-CH protein IX; membrane-associated RING finger protein 9; MARCH-IX

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