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mapre1

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Official Full Name
microtubule-associated protein, RP/EB family, member 1
Background
End binding protein 1 and may play a part in regulation of microtubule dynamics in the mammalian cells. EB1 could also play a role in the regulation of microtubule assembly and stability. EB1 is essential for proper cilia assembly in fibroblasts. EB1 has been shown to excite spontaneous nucleation and microtubule growth. APC gene mutation and the loss of negatively regulating WNT signaling is thought to play a role in the proliferation changes of cancer. The loss of association with EB1 could contribute to the development of certain cancers.
Synonyms
MAPRE1; microtubule-associated protein, RP/EB family, member 1; microtubule-associated protein RP/EB family member 1; adenomatous polyposis coli binding protein EB1; EB1; end-binding protein 1; APC-binding protein EB1; adenomatous polyposis coli-binding protein EB1; MGC117374; MGC129946