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map3k15

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Official Full Name
mitogen-activated protein kinase kinase kinase 15
Background
The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family. These family members function in a protein kinase signal transduction cascade, where an activated MAPK kinase kinase (MAP3K) phosphorylates and activates a specific MAPK kinase (MAP2K), which then activates a specific MAPK. This MAP3K protein plays an essential role in apoptotic cell death triggered by cellular stresses.
Synonyms
MAP3K15; mitogen-activated protein kinase kinase kinase 15; bA723P2.3; FLJ16518; MAPK/ERK kinase kinase 15; MEK kinase 15; MEKK 15; Mitogen activated protein kinase kinase kinase 15; OTTHUMP00000183504; OTTHUMP00000183505; OTTHUMP00000224565; apoptosis signal-regulating kinase 3; ASK3

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