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maml1

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Official Full Name
mastermind-like 1 (Drosophila)
Background
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq, Jul 2008]
Synonyms
MAML1; mastermind-like 1 (Drosophila); Mam1; Mam-1; mastermind-like protein 1; mastermind homolog