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magea11

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Official Full Name
melanoma antigen family A, 11
Background
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
MAGEA11; melanoma antigen family A, 11; MAGE11; melanoma-associated antigen 11; cancer/testis antigen family 1; member 11; CT1.11; MAGE 11; MAGE 11 antigen; MAGEA 11; melanoma associated antigen 11; MGC10511; MAGE-11 antigen; cancer/testis antigen 1.11; c; cancer/testis antigen family 1, member 11; MAGE-11; MAGEA-11