The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
MAD2L1BP; MAD2L1 binding protein; MAD2L1-binding protein; CMT2; dJ261G23.1; KIAA0110; Caught by MAD2 protein; MAD2L1 binding protein isoform 2; MGC11282; OTTHUMP00000016496; RP1 261G23.6; OTTHUMP00000221652; RP1-261G23.6; CMT2, RP1-261G23.6