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lyar

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Official Full Name
Ly1 antibody reactive
Background
LYAR, also known as Ly1 antibody reactive clone, has been found to regulate the intracellular strength that is stimulated by both T and B cell antigen receptors. It is essential for immune tolerance and certain changes to its function could stimulate the development of autoreactivity. LYAR is important in the immunological synapse and functions to inhibit the T cell response. LYAR is highly expressed in indifferentiated embryonic stem cells and may be important in maintaining the stem cell identity.
Synonyms
LYAR; Ly1 reactive clone; cell growth-regulating nucleolar protein; protein expressed in male leptotene and zygotene spermatocytes 264; MLZ-264; Ly1 reactive homolog (mouse); ZLYAR; FLJ20425; Ly1 antibody reactive homolog (mouse); zgc:65749