The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
LRRN2; leucine rich repeat neuronal 2; leucine rich repeat neuronal 5 , LRRN5; leucine-rich repeat neuronal protein 2; fibronectin type III; immunoglobulin and leucine rich repeat domain 7; FIGLER7; GAC1; leucine rich and ankyrin repeats 1; LRANK1; Fibronectin type III immunoglobulin and leucine rich repeat domain 7; GAC 1; Glioma amplified on chromosome 1; Glioma amplified on chromosome 1 protein; Leucine rich repeat neuronal 5; Leucine rich repeat neuronal protein 2; Leucine rich repeat neuronal protein 5; LRANK 1; LRRN 2; LRRN 5; OTTHUMP00000034222; OTTHUMP00000035083; leucine-rich repeat neuronal protein 5; fibronectin type III, immunoglob; LRRN5; GAC1, LRRN5, LRANK1, FIGLER7