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lrpprc

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Official Full Name
leucine-rich pentatricopeptide repeat containing
Background
This gene encodes a leucine-rich protein that has multiple pentatricopeptide repeats (PPR). The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization, vesicular transport, or in transcriptional regulation of both nuclear and mitochondrial genes. The protein localizes primarily to mitochondria and is predicted to have an N-terminal mitochondrial targeting sequence. Mutations in this gene are associated with the French-Canadian type of Leigh syndrome. [provided by RefSeq, Mar 2012]
Synonyms
LRPPRC; leucine-rich pentatricopeptide repeat containing; LSFC; GP130; LRP130; CLONE-23970; leucine-rich PPR motif-containing protein, mitochondrial; LRP 130; 130 kDa leucine-rich protein; leucine-rich PPR-motif containing; mitochondrial leucine-rich PPR motif-containing protein; im:7150924; im:7151572; wu:fj38h02

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