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lpl

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Official Full Name
lipoprotein lipase
Background
LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.
Synonyms
LIPD; HDLCQ11; EC 3.1.1.34; LPL; lipoprotein lipase; MGC137861; OTTHUMP00000034806; triacylglycerol lipase; adipose lipoprotein lipase; fb62e04; fc49b03; wu:fb62e04; wu:fc49b03

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