Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and;at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function;(see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor;tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may;initiate stimulatory cascades (see LILRA1, MIM 604810). One member of subfamily A (LILRA3) lacks a transmembrane;region and is presumed to be a soluble receptor (Borges et al., 1997 (PubMed 9548455)).
LILRA3; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3; leukocyte immunoglobulin-like receptor subfamily A member 3; CD85e; HM31; HM43; ILT6; LIR 4; LIR4; CD 85E; CD85 antigen-like family member E; CD85e antigen; e3; HM 31; HM 43; ILT 6; ILT-6; Immunoglobulin like transcript 6; Immunoglobulin-like transcript 6; Leucocyte immunoglobulin like receptor; Leukocyte immunoglobulin like receptor 4; Leukocyte immunoglobulin like receptor A3; Leukocyte immunoglobulin like receptor subfamily A (without TM domain) member 3; Leukocyte immunoglobulin like receptor subfamily A member 3; Leukocyte immunoglobulin-like receptor 4; LILRA 3; LIR-4; LIRA3_HUMAN; Monocyte inhibitory receptor HM43/HM31; OTTHUMP00000067955; OTTHUMP00000067956; OTTHUMP00000067957; leucocyte immunoglobulin-like receptor; monocyte inhibitory recept; leukocyte immunoglobulin-like receptor A3