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Official Full Name
luteinizing hormone beta polypeptide
Background
Luteinizing Hormone is a member of the glycoprotein hormone beta chain family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. Luteinizing Hormone is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.
Synonyms
CGB4; hLHB; LSH-B; Luteinizing Hormone (hLH) Beta Core Fragment; luteinizing hormone beta polypeptide; LHB; luteinizing hormone, beta polypeptide; zgc:92312; LH beta 2; luteinizing hormone beta 2; luteinizing hormone beta-subunit