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lbr

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Official Full Name
lamin B receptor
Background
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Synonyms
LBR; lamin B receptor; PHA; LMN2R; TDRD18; DHCR14B; lamin-B receptor; tudor domain containing 18; integral nuclear envelope inner membrane protein; MGC9041; FLJ43126; sb:cb406; zgc:86649; wu:fb75h08; wu:fc47b04; wu:fd36b07

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