The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
LAIR1; leukocyte-associated immunoglobulin-like receptor 1; leukocyte associated Ig like receptor 1; CD305; 5133400O11Rik; D7Bwg0421e; hLAIR1; LAIR 1; LAIR-1; LAIR1 protein; LAIR1_HUMAN; Leukocyte associated immunoglobulin like receptor 1; OTTHUMP00000068183; OTTHUMP00000068184; OTTHUMP00000068185; OTTHUMP00000068186; OTTHUMP00000068187; leukocyte-associated Ig-like receptor 1