The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
KRT85; keratin 85; hHb5; Basic Hair Keratin K85; HB5; Hb-5; KRTHB5; keratin, type II cuticular Hb5; K85; keratin-85; hair keratin K2.12; type-II keratin Kb25; keratin, hair, basic, 5; hard keratin, type II, 5; type II hair keratin Hb5.