The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.
KRT82; keratin 82; hHb2; Basic Hair Keratin K82; KRTHB2; Hb-2; HB2; keratin, type II cuticular Hb2; K82; keratin-82; type-II keratin Kb22; keratin, hair, basic, 2; hard keratin, type II, 2; type II hair keratin Hb2.