This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.
KRT27; keratin 27; KRT25C; keratin, type I cytoskeletal 27 K27; K25C; CK-27; keratin-27; keratin 25C; keratin-25C; cytokeratin-27; type I inner root sheath specific keratin 25 irs3; type I inner root sheath-specific keratin-K25irs3; OTTHUMP00000164526; keratin K27; K25irs3 KRT27; K25irs3