This gene encodes a BTB and kelch domain containing protein and belongs to the kelch repeat domain containing superfamily of proteins. The encoded protein functions as an adaptor protein that complexes with Cullin 3 and other proteins to form the Cullin 3-based E3 ubiquitin-protein ligase complex. This complex is necessary for proper chromosome segregation and completion of cytokinesis. Alternate splicing results in multiple transcript variants.
KLHL13; kelch-like 13 (Drosophila); BKLHD2, BTB and kelch domain containing 2, KIAA1309 , KIAA1309; kelch-like protein 13; FLJ10262; BKLHD2; BTB and kelch domain containing 2; BTB and kelch domain containing 2 KIAA1309; BTB and kelch domain containing protein 2; Kelch like 13 (Drosophila); Kelch like protein 13; KIAA1309; MGC74791; OTTHUMP00000023881; OTTHUMP00000023882; OTTHUMP00000023883; OTTHUMP00000023885; OTTHUMP00000215715; kelch-like 9 (Drosophila); kelch-like 13; kelch-like family member 13; wu:fc15b07; zgc:163008