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klhdc3

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Official Full Name
kelch domain containing 3
Background
The protein encoded by this gene contains six repeated kelch motifs that are structurally similar to recombination activating gene 2 (RAG2), a protein involved in the activation of the V(D)J recombination. In mouse, this gene is found to express specifically in testis. Its expression in pachytene spermatocytes is localized to cytoplasma and meiotic chromatin, which suggests that this gene may be involved in meiotic recombination. Alternatively spliced transcript variants have been found.
Synonyms
KLHDC3; kelch domain containing 3; kelch domain-containing protein 3; dJ20C7.3; hPeas; PEAS; KLDC3_HUMAN; Protein Peas; RP1-20C7.3; Testis intracellular mediator protein; PEAS, dJ20C7.3, RP1-20C7.3, KLHDC3; zgc:85727

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