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klf14

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Official Full Name
Kruppel-like factor 14
Background
This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.
Synonyms
KLF14; Kruppel-like factor 14; Krueppel-like factor 14; BTEB5; BTE-binding protein 5; transcription factor BTEB5; basic transcription element-binding protein 5

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