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klf11

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Official Full Name
Kruppel-like factor 11
Background
The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
KLF11; Kruppel-like factor 11; TGFB inducible early growth response 2 , TIEG2; Krueppel-like factor 11; MODY7; Tieg3; TIEG-2; TGFB-inducible early growth response protein 2; transforming growth factor-beta-inducible early growth response protein 2; FKLF; FKLF1; TIEG2