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kcnj4

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Official Full Name
potassium inwardly-rectifying channel, subfamily J, member 4
Background
Various potassium channels are involved with electrical signaling in the nervous system. One class is activated by depolarization; whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. This KIR2.3 protein is an integral membrane protein and member of the inward rectifier potassium channel family. It has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for its gene.
Synonyms
KCNJ4; potassium inwardly-rectifying channel, subfamily J, member 4; inward rectifier potassium channel 4; HIR; hIRK2; HRK1; IRK3; Kir2.3; inward rectifier K+ channel Kir2.3; inward rectifier K(+) channel Kir2.3; hippocampal inward rectifier potassium cha; hippocampal inward rectifier potassium channel; potassium channel, inwardly rectifying subfamily J member 4; IRK-3; MGC142066; MGC142068