Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. This gene is not expressed in differentiating myoblasts. Alternative splicing results in three transcript variants encoding distinct isoforms.
KCNH5; potassium voltage-gated channel, subfamily H (eag-related), member 5; potassium voltage-gated channel subfamily H member 5; eag2; H EAG2; Kv10.2; hEAG2; potassium channel HEAG2; ether-a-go-go potassium channel 2; voltage-gated potassium channel EAG; voltage-gated potassium channel EAG2; ether-a-go-go-related potassium channel 2; voltage-gated potassium channel subunit Kv10.2; H-EAG2