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kcnh1

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Official Full Name
potassium voltage-gated channel, subfamily H (eag-related), member 1
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.
Synonyms
KCNH1; potassium voltage-gated channel, subfamily H (eag-related), member 1; potassium voltage-gated channel subfamily H member 1; eag; eag1; h eag; Kv10.1; Voltage gated potassium channel subunit Kv10.1; MGC124420; MGC142269; EAG channel 1; Ether a go go potassium channel 1; Ether-a-go-go potassium channel 1; h-eag; hEAG1; KCNH1_HUMAN; M eag; MGC124419; Potassium voltage gated channel subfamily H (eag related), member 1; Voltage-gated potassium channel subunit Kv10.1; OTTHUMP00000034451; OTTHUMP00000034569; ether-a-go-go, Drosophila, homolog of