Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
KARS; lysyl-tRNA synthetase; lysine--tRNA ligase; KARS2; lysine tRNA ligase; lysRS; KRS; CMTRIB; KIAA0070; CMTRIB, KARS2, KIAA0070, KRS, KARS; cb530; zgc:92483; wu:fa16h02