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jdp2

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Official Full Name
Jun dimerization protein 2
Background
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Synonyms
JDP2; Jun dimerization protein 2; JUNDM2; progesterone receptor co-activator; fk87c02; zgc:92851; wu:fk87c02