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iscu

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Official Full Name
iron-sulfur cluster assembly enzyme
Background
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins.;They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors,;chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster;scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance;and myoglobinuria.
Synonyms
ISCU; iron-sulfur cluster scaffold homolog (E. coli); iron-sulfur cluster assembly enzyme ISCU, mitochondrial; mitochondrial; 2310020H20Rik; HML; hnifU; Iron sulfur cluster assembly enzyme ISCU mitochondrial; Iron sulfur cluster scaffold homolog (E. coli); Iron sulfur cluster scaffold homolog; Iron-sulfur cluster assembly enzyme ISCU; IscU iron sulfur cluster scaffold homolog; ISCU_HUMAN; ISU2; MGC74517; NIFU; NifU like N terminal domain containing; NifU like N terminal domain containing protein; NifU like protein; NifU-like N-terminal domain-containing protein; NifU-like protein; NIFUN; Nitrogen fixation cluster like; OTTHUMP00000238760; OTTHUMP00000238761; OTTHUMP00000238762; OTTHUMP00000238764; OTTHUMP00000238765; IscU iron-sulfur cluster scaffold homolog; RGD1309562; IscU iron sulfur cluster scaffold homolog (E. coli) , NifU like N terminal domain containing , NIFUN; NifU-like N-terminal domain containing