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irs2

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Official Full Name
insulin receptor substrate 2
Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin,;insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine;kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase;upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Synonyms
IRS2; insulin receptor substrate 2; IRS-2