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irs1

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Official Full Name
insulin receptor substrate 1
Background
This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]
Synonyms
IRS1; insulin receptor substrate 1; HIRS-1; IRS-1; HIRS 1