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ints6

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Official Full Name
integrator complex subunit 6
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3 end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms
INTS6; integrator complex subunit 6; DDX26, DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; DBI 1; DDX26A; DICE1; HDB; INT6; Notchl2; DBI-1; DBI1; DDX26; DEAD box protein; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 26; Deleted in cancer 1; DKFZp434B105; INT6_HUMAN; INTS 6; OTTHUMP00000018439; OTTHUMP00000215034; OTTHUMP00000215036; Protein DDX26; Protein deleted in cancer 1; RNA helicase HDB; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26