Tel: 1-631-626-9181 (USA)   44-207-097-1828 (Europe)

CBpromise   

Our promise to you:
Guaranteed product quality, expert customer support.

24x7 CUSTOMER SERVICE
CONTACT US TO ORDER

ino80

Bookmark and Share
Official Full Name
INO80 complex subunit
Background
DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.
Synonyms
4632409L19Rik; DNA helicase INO80; hINO80; homolog of yeast INO80; INO80; INO80 complex subunit A; INO80 homolog; INO80A; INOC1; KIAA1259; Putative DNA helicase INO80 complex homolog 1; INO80 complex subunit; INO80 complex homolog 1; si:ch211-244p18.3