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impdh1

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Official Full Name
IMP (inosine 5'-monophosphate) dehydrogenase 1
Background
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Synonyms
IMPDH1; IMP (inosine 5-monophosphate) dehydrogenase 1; IMPD; RP10; IMPD1; LCA11; sWSS2608; inosine-5-monophosphate dehydrogenase 1; IMPD 1; IMPDH 1; IMPDH-I; IMP dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1

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