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il26

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Official Full Name
interleukin 26
Background
Interleukin 26 (IL-26) is a homodimer cytokine belonging to the IL-10 family that is expressed in certain herpesvirus-transformed T cells but IL-26 induces rapid phosphorylation of the transcription factors STAT1 and STAT3,Which enhance IL-10 and IL-8 secretion and as expression of the CD54 molecule on the surface of epithelial cells. IL-26's function in human disease is unknown, however research has found that IL-26 expression is up-regulated in active Crohn's disease, and therefore may play an active role along with Th17 cells in various autoimmune diseases.
Synonyms
IL26; interleukin 26; interleukin-26; AK155; IL 26; IL-26; zgc:194942; Ifnphi5

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