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ikbke

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Official Full Name
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
Background
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling;pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed;in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 (PubMed 19481526)).
Synonyms
IKBKE; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; inhibitor of nuclear factor kappa-B kinase subunit epsilon; IKK i; IKKE; KIAA0151; IKK-epsilon; I-kappa-B kinase epsilon; inducible IkappaB kinase; IKK-related kinase epsilon; inducible I kappa-B kinase; IKKI; IKK-E; IKK-i; MGC125294; MGC125295; MGC125297; zgc:100844