Interferon alpha (IFN alpha) is a glycosylated protein which is produced by many cell types such as monocytes, macrophages, ?broblasts in response to virus infection, nucleic acid induction, glucocorticoid hormones. Some of the other biological effects, including antitumor and immunomodulatory activities IFN-alpha ’s most important function is the antiviral activity. It enhances the expression of MHC proteins by increasing the presentation of antigen peptides. Some other biological processes involving IFN alpha are:induction of apoptosis, signal transduction, in?ammatory response. IFN alpha activates cytotoxic T-cells. IFN alpha binds to its receptors, which upon dimerisation, activate the JAK-STAT pathway.
IFNA2; interferon, alpha 2; interferon alpha-2; alpha 2a interferon; IFN alphaA; IFNA; interferon alpha 2b; interferon alpha A; leIF A; IFN-alpha-2; alpha-2a interferon; INFA2; IFNA2B; IFN-alphaA; MGC125764; MGC125765