Official Full Name
hematopoietic SH2 domain containing
T-cell activation requires 2 signals: recognition of antigen by the T-cell receptor (see TCR; MIM 186880) and a;costimulatory signal provided primarily by CD28 (MIM 186760) in naive T cells. HSH2 is a target of both of these;signaling pathways (Greene et al., 2003 (PubMed 12960172)).
HSH2D; hematopoietic SH2 domain containing; hematopoietic SH2 domain-containing protein; ALX; FLJ14886; HSH2; hematopoietic SH2 protein; adaptor in lymphocytes of unknown function X; wu:fk78a10; zgc:113273; hematopoietic SH2 domain-containing protein homolog